Pseudogene similar to part of aldo-keto reductase family 1, member B1 (ENSG00000225297)

This entry, ENSG00000225297, is a pseudogene with high sequence similarity to part of the aldo-keto reductase family 1, member B1 (also known as aldose reductase, gene symbol AKR1B1), but lacks the capacity to encode a functional protein product due to disabling mutations or loss of regulatory elements. Pseudogenes are common in the genome and typically do not participate in any cellular function, although rare pseudogenes in some gene families can produce regulatory RNAs or interfere with related transcripts. No such activity or functional role has been described for this specific locus. Pseudogenes are not considered direct therapeutic targets, nor do they have established disease roles or drug interactions. They may cause artifacts or confusion in molecular genetics studies if mistaken for their functional homologs, but generally have no clinical utility.

Other names

Pseudogene similar to part of aldo-keto reductase family 1, member B1 (provided by source databases)Aldose reductase pseudogene (implied by description)AKR1B1 pseudogene (implied by homology; not a standard alias)

None. As no drugs interact with this pseudogene, there are no mechanisms of action