Pseudogene similar to part of ATP-dependent metalloprotease YME1-like 1

This target refers to a *pseudogene* with sequence similarity to the protein-coding YME1-like 1 ATPase (YME1L1)[2][4]. Pseudogenes are DNA sequences homologous to functional genes but typically lack the capability to encode a functional protein product[2][4]. Most pseudogenes arise from gene duplication or retrotransposition events and usually acquire disabling mutations (e.g., premature stop codons, frameshifts)[2][4]. As a pseudogene, ENSG000002243552 is not expressed as a functional protein and is not considered a direct therapeutic target such as an enzyme, receptor, ion channel, or transporter[2][4]. While some pseudogenes are transcribed and may be involved in regulating other genes (e.g., as competitive endogenous RNAs in cancer), there is no evidence that this particular pseudogene has such a role[6]. YME1L1, the functional gene this pseudogene resembles, is an ATP-dependent metalloprotease responsible for mitochondrial protein quality control, morphology, and cell survival—but this function is not attributed to the pseudogene[1][3][5].

Other names

YME1L1 pseudogenepseudogene similar to YME1L1