Pseudogene similar to part of constitutive photomorphogenic protein, COP1

ENSG00000228143 is a pseudogene with sequence similarity to a portion of the constitutive photomorphogenic protein COP1, an E3 ubiquitin ligase involved in regulated protein degradation and photomorphogenesis in plants. This pseudogene itself does not encode a functional protein and is not known to be expressed or to have a direct biological, pathological, or therapeutic role in humans. Pseudogenes are generally considered non-functional gene copies or gene fragments, although in rare cases some pseudogenes can play regulatory roles or contribute to disease by affecting gene expression. However, there is no evidence for such a function for ENSG00000228143 at present, and it is not considered a therapeutic target. This entry is labeled a pseudogene and is not a functional protein-coding gene. COP1 (constitutive photomorphogenic protein 1) itself is well-characterized in plants (as a central regulator of light-dependent development, acting as an ubiquitin ligase), but this pseudogene does not represent a human therapeutic target and should not be confused with functional homologs.

Other names

Pseudogene similar to COP1COP1 pseudogeneENSG00000228143