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Pseudogene similar to part of cytochrome c oxidase subunit 7A1 polypeptide 1 (ENSG00000219604)

Target
ENSG00000219604
Molecular classification
Pseudogene
01

Overview

ENSG00000219604 corresponds to a human pseudogene, similar to part of cytochrome c oxidase subunit VIIa polypeptide 1 (COX7A1). A pseudogene is a genomic DNA sequence similar to a functional gene but typically non-coding due to disablements such as stop codons or frameshifts. While its parental gene, COX7A1, encodes a muscle isoform of subunit VIIa of cytochrome c oxidase (Complex IV of the mitochondrial respiratory chain, critical for oxidative phosphorylation in heart and skeletal muscle)[5][3], the pseudogene version does not produce a functional protein and is not considered a receptor, enzyme, transporter, or any classical druggable target. Pseudogenes like this one may have regulatory or epigenetic functions at the RNA level, though specific roles are rarely validated and none are directly attributed to this entity. There are no known interacting drugs, disease-specific roles, biomarker status, or therapeutic challenges associated with this pseudogene. The “target” is most accurately described as a non-coding pseudogene rather than a true molecular target for therapies or diagnostics[2][4][6]. This entry is *not* a protein, receptor or true gene product with clinical drug targeting potential, and is accordingly flagged as not a canonical therapeutic target. **Key interpretation:** The query appears to conflate a pseudogene (non-protein-coding, not a drug target) with a canonical target, so "is_incorrect" is true, and all structured fields reflect its non-target, non-functional gene status.

Other names
cytochrome c oxidase subunit VIIa polypeptide 1 pseudogeneCOX7A1 pseudogene
02

Mechanism of action

None; no mechanism as a drug target

03

Biological functions

Potential non-coding RNA functions (e.g., microRNA decoy, regulation of parental gene via antisense or competing endogenous RNA mechanisms)not a protein-coding enzyme or structural subunit
04

Disease associations

Other (Potential regulatory roles have been hypothesized for pseudogenes in cancer or other diseases, but there is no evidence this specific pseudogene acts as a disease gene or direct disease driver)

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