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The ENSG00000232663 gene is a human pseudogene, similar to the protein-coding gene for Cytochrome c oxidase subunit II (MT-CO2). Pseudogenes are DNA sequences that resemble functional genes but have lost their protein-coding ability due to mutations, truncations, or lack of regulatory elements[1][9][12]. This particular pseudogene represents a segment with high similarity to the mitochondrial gene for Cytochrome c oxidase subunit II, a key enzyme in the mitochondrial electron transport chain[11], but, unlike the functional gene, it does not encode a protein nor is it involved in respiratory chain activity. Pseudogenes typically have no known biological activity, are not considered therapeutic targets, and do not interact with drugs or function as biomarkers in clinical practice[1][9][12].
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