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Pseudogene similar to part of GTF2I repeat domain containing 1

Molecular classification: Other (Pseudogene; not a member of major molecular families such as receptors, enzymes, etc.)

Overview

ENSG00000228829 is a pseudogene similar to part of GTF2I repeat domain containing 1 (GTF2IRD1). Pseudogenes are DNA sequences that resemble protein-coding genes but are nonfunctional due to mutations or lack of regulatory elements. Unlike their functional counterparts, pseudogenes do not produce proteins and therefore are not considered valid therapeutic targets, receptors, or druggable molecules[1]. While the functional parent gene, GTF2IRD1, is a transcription factor associated with transcriptional regulation and certain genetic syndromes, this pseudogene does not have known biological activity or medical relevance[1][4][5]. Key Clarification: ENSG00000228829 is not a functional gene or therapeutic target. The correct target for drug discovery in this family would be the protein-coding gene GTF2IRD1 (GTF2I repeat domain containing 1), not this pseudogene.

Other names: GTF2IRD1 pseudogenepseudogene similar to GTF2IRD1

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