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ENSG00000224412 is a pseudogene with sequence similarity to the heat shock 10kDa protein 1 (chaperonin 10, HSPE1). Pseudogenes are nonfunctional segments of DNA with high homology to functional genes but lack the ability to encode functional proteins. While pseudogenes sometimes have regulatory RNA functions or can complicate genetic analyses, this specific pseudogene has not been linked to protein function, disease roles, or therapeutic applications. Most functional studies and therapeutic targeting focus on the parent gene (HSPE1) or other heat shock proteins, not pseudogene homologs.
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