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Pseudogene similar to part of laminin receptor 1

Molecular classification
Other
01

Overview

ENSG00000234087 is annotated as a pseudogene similar to part of laminin receptor 1 (LAMR1, also known as ribosomal protein SA, RPSA). By definition, a pseudogene is a genomic DNA sequence similar to a known gene but typically non-functional due to mutations or sequence truncations; it does not encode a functional protein and is not considered a biological or therapeutic target[1]. There is no evidence it produces a functional product, participates in signaling, or is associated with disease or drug response. Additional context: The functional gene encoding the 67 kDa laminin receptor (LAMR1, RPSA) is a bona fide receptor involved in cell adhesion, extracellular matrix interactions, and pathogen binding, but ENSG00000234087 does not correspond to a functional copy of this gene[3][4]. This pseudogene itself is not a therapeutic target, has no established function, and there are no known drug interactions or biomarker roles attributed to it[1]. Note: If the intention was to refer to the functional 67 kDa laminin receptor/RPSA gene, you should instead use "ribosomal protein SA" or "LAMR1/RPSA" (gene ID: 3921 in humans)[4]; that gene is a cell surface receptor, with confirmed biological functions and relevance in several diseases[3][4]. The current entry ENSG00000234087 is not a functional gene[1].

Other names
Pseudogene similar to part of LAMR1ENSG00000234087

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