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Pseudogene similar to part of makorin ring finger protein 1
- Molecular classification
- Other, pseudogene
01
Overview
This gene entry represents a pseudogene similar to part of makorin ring finger protein 1, annotated as LOC100420298 (ENSG00000251579). Pseudogenes like this are typically derived from protein-coding genes—here, the ancestral Makorin ring finger protein 1 (MKRN1). They arise by duplication or retrotransposition and generally lack promoters or necessary regulatory elements, making them transcriptionally silent. Molecular studies show that MKRN1-pseudogenes are not transcribed or imprinted in humans or mice, and do not participate in the stabilization or regulation of MKRN1 mRNA. Experimental disruption of MKRN1-pseudogenes does not result in observable disease or physiological phenotypes. Thus, this locus is not a therapeutic or diagnostic target, and does not have molecular functions or drug interactions associated with protein-coding genes.
- Other names
- LOC100420298ENSG00000251579pseudogene similar to part of makorin ring finger protein 1
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