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pseudogene similar to part of NADH dehydrogenase 6

Molecular classification
Other (Pseudogene)
01

Overview

ENSG00000228667 is annotated as a pseudogene similar to part of NADH dehydrogenase 6 (ND6). Pseudogenes are typically DNA sequences that resemble known genes but are considered nonfunctional, usually due to the accumulation of disabling mutations or lack of necessary transcription signals. This pseudogene is not known to encode a functional protein, nor is it recognized as a therapeutic target such as a receptor, enzyme, transporter, or transcription factor. There is no evidence supporting a biological function, role in disease, or drug interactions for this particular pseudogene. Notably, the functional mitochondrial ND6 gene (MT-ND6) itself encodes a subunit of Complex I in the mitochondrial respiratory chain, which is clinically significant; however, pseudogenes of ND6 are not known to share these roles. Note: - ENSG00000228667 refers to a pseudogene, not a functional gene or protein. It is not considered a druggable target. - No alternative names, drug interactions, biological roles, or clinical utility are associated with this pseudogene. - This entry is not considered a standard target for pharmacology or disease research. Summary of assessment: This entry is a pseudogene, not a functional gene product or pharmacological target. There are therefore no abbreviations, no established aliases, no molecular function, no drug interactions, and no roles in disease or therapy. Pseudogenes are generally not considered in drug development or as therapeutic targets. The information provided here should allow automated parsing for structured database ingestion or exclusion.

Other names
ND6 pseudogenepseudogene of NADH dehydrogenase subunit 6
02

Biological functions

Other (No established function; pseudogenes usually considered nonfunctional)
03

Disease associations

Other (No evidence of disease involvement for this specific pseudogene; note that functional ND6 gene mutations are associated with diseases such as Leber hereditary optic neuropathy and Leigh syndrome, but pseudogenes typically are not implicated in these disorders)

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