Pseudogene similar to part of NADH dehydrogenase subunit 6

ENSG00000228525 is a pseudogene that shares partial sequence similarity with the coding sequence for NADH dehydrogenase subunit 6 (ND6), a gene involved in mitochondrial electron transport as part of Complex I. Pseudogenes such as ENSG00000228525 generally lack coding potential, do not produce functional proteins, and have no direct biological or therapeutic relevance. There is no evidence this pseudogene is involved in disease, used as a biomarker, or considered a target for drugs or research interventions[1]. Key distinctions: - This is not the active mitochondrial complex I gene (MT-ND6)[4][8], nor a nuclear gene encoding a functional subunit of NADH dehydrogenase. - Functional ND6 and related mitochondrial genes are implicated in disorders like Leber hereditary optic neuropathy and Leigh syndrome[4][8], but this pseudogene is not. Summary: ENSG00000228525 is simply a genomic sequence classified as a pseudogene and is not a molecular target, drug target, or implicated in disease biology[1].