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ENSG00000233494 refers to a pseudogene in the human genome that is similar to a segment of the plasminogen (PLG) gene but is nonfunctional and does not encode a protein[1]. Pseudogenes such as this typically arise from duplication or retrotransposition but accumulate disabling mutations, rendering them inactive. While most pseudogenes do not have a direct biological function, some can regulate their parent genes or participate as noncoding RNAs in gene regulatory networks; however, no specific regulatory function has been documented for ENSG00000233494[2]. Pseudogenes are not considered drug targets or disease biomarkers in clinical practice.
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