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ENSG00000228957 encodes a pseudogene that has sequence similarity to a region of the functional RALGDS gene (Ral guanine nucleotide dissociation stimulator)[3]. Unlike RALGDS, which is a protein-coding gene serving as a guanine nucleotide exchange factor in signal transduction[1][2], pseudogenes lack the ability to encode functional proteins but may produce non-coding RNAs with potential regulatory effects[4][5]. The biological and clinical significance of most pseudogenes is currently unclear, though some may modulate expression of related genes via lncRNA or miRNA “decoy” functions[4][5]. There is no evidence that ENSG00000228957 is directly involved in disease or therapeutic interventions.
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