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Pseudogene similar to part of RAS guanyl releasing protein 2 (No canonical abbreviation, as pseudogenes typically lack standardized abbreviations.)
- Target
- No canonical abbreviation, as pseudogenes typically lack standardized abbreviations.
- Molecular classification
- Pseudogene
01
Overview
ENSG00000249472 is a **pseudogene** located on human chromosome 11, designated as "pseudogene similar to part of RAS guanyl-releasing protein 2 (calcium and DAG-regulated)"[5][4]. The sequence is related to the functional gene **RASGRP2**, which encodes a guanine nucleotide exchange factor activating small GTPases including Ras and Rap1[2][6][8]. However, unlike its protein-coding counterpart, this pseudogene lacks the ability to encode a functional protein and is not directly implicated in physiological processes or diseases. Pseudogenes generally arise from duplication or retrotransposition of functional genes and acquire disabling mutations or regulatory mechanisms preventing protein expression. This locus is not considered actionable as a therapeutic target.
- Other names
- Pseudogene similar to part of RAS guanyl-releasing protein 2ENSG00000249472
02
Mechanism of action
None.
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