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ENSG00000226532 is a pseudogene that shows sequence similarity to a portion of the human ribosomal protein, large, P1 (RPLP1) gene, but does not produce a functional protein product[7][2][5]. As a processed pseudogene, it arose via retrotransposition and may lack the necessary regulatory elements for transcription and translation. While most pseudogenes have traditionally been considered "junk DNA," some are now known to regulate their functional gene counterparts via noncoding RNAs, though no such function has been specifically documented for this pseudogene. This gene is not considered a therapeutic target and does not have known pharmacological or clinical relevance[7][2][4]. There are no drugs, biomarkers, or recognized disease roles associated with ENSG00000226532; it is mainly of interest as a genomic annotation and an example of ribosomal protein gene family pseudogenization[7][5][2].
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