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Pseudogene similar to part of ribosomal protein, large, P1

Molecular classification
Pseudogene, Processed pseudogene, Large ribosomal subunit protein-related
01

Overview

ENSG00000226532 is a pseudogene that shows sequence similarity to a portion of the human ribosomal protein, large, P1 (RPLP1) gene, but does not produce a functional protein product[7][2][5]. As a processed pseudogene, it arose via retrotransposition and may lack the necessary regulatory elements for transcription and translation. While most pseudogenes have traditionally been considered "junk DNA," some are now known to regulate their functional gene counterparts via noncoding RNAs, though no such function has been specifically documented for this pseudogene. This gene is not considered a therapeutic target and does not have known pharmacological or clinical relevance[7][2][4]. There are no drugs, biomarkers, or recognized disease roles associated with ENSG00000226532; it is mainly of interest as a genomic annotation and an example of ribosomal protein gene family pseudogenization[7][5][2].

Other names
Pseudogene similar to part of RPLP1ENSG00000226532
02

Biological functions

Potential regulatory roles through noncoding RNA mechanisms as seen in some pseudogenes, such as acting as microRNA decoys or forming siRNA, but no specific function is assigned for this pseudogene
03

Disease associations

No direct disease associations described; some pseudogenes may be deregulated in diseases like cancer and diabetes, but there is no disease linkage specifically noted for this pseudogene

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