Pseudogene similar to part of ribosomal protein S13

This gene locus, ENSG00000226110, is annotated as a pseudogene resembling part of ribosomal protein S13 (RPS13)[1]. Pseudogenes are copy-like sequences of genes that have lost protein-coding ability due to disruptive mutations, such as premature stop codons or frameshifts[2][4][6]. Although pseudogenes like this one often retain high sequence similarity to their functional parent genes, in this case ribosomal protein S13, they do not produce functional proteins and are generally not involved in normal cellular processes[2][4]. Occasionally, some pseudogenes can exert effects through RNA-mediated regulation, but no specific regulatory function has been reported for ENSG00000226110[4][6]. This pseudogene should not be considered a true therapeutic target; its presence can complicate molecular genetic studies due to sequence similarity with the parent gene, potentially causing issues like PCR bias[4]. There is no evidence of it being involved in disease mechanisms, drug interactions, or serving as a biomarker[1][4][6]. In summary, Pseudogene similar to part of ribosomal protein S13 is a gene sequence homologous to RPS13 but unable to encode functional ribosomal protein S13[1][2][3]. It is not a therapeutic target or functional molecular entity[2][4][6]. There are no known drugs, disease roles, or functional annotations specific to this pseudogene[1][4][6]. If structured data for the actual ribosomal protein S13 gene (RPS13) is needed, it should be specified, as that is a separate, functional protein-encoding gene[3][5].

Other names

RPS13Pprocessed pseudogeneribosomal protein S13 pseudogene