Pseudogene similar to part of septin 13 (SEPT13 pseudogene)

ENSG00000203462 encodes a pseudogene that is similar in sequence to a portion of the **septin 13** (SEPT13) gene, but it is not expected to encode a functional protein product[1][3]. Pseudogenes like this commonly arise from the duplication or partial duplication of protein-coding genes, or by retrotransposition, and generally harbor mutations (such as frameshifts or premature stop codons) that prevent proper transcription or translation into a functional protein[3]. While traditionally considered "junk DNA," some pseudogenes are now recognized as potentially having functional roles in gene regulation. This regulation can occur through the production of noncoding RNAs that may act as decoys for microRNAs, produce small interfering RNAs, or modulate the expression of related coding genes[2]. However, there is no direct evidence or functional annotation indicating that this particular pseudogene acts as a receptor, enzyme, transporter, or other canonical therapeutic target, nor that it is associated with any known drugs, mechanisms of action, biomarkers, or therapeutic safety issues[1][3]. Pseudogenes can complicate molecular genetics studies as they may be mis-annotated as functional genes or may interfere with genetic assays such as PCR due to sequence similarity with coding genes[3].

Other names

SEPT13 pseudogenePseudogene similar to SEPT13