Pseudogene similar to part of V-set and immunoglobulin domain containing 6

This locus represents a pseudogene, which contains a sequence similar to part of the V-set and immunoglobulin domain containing 6 (VSIG6). Pseudogenes are stretches of DNA that resemble known genes but are generally non-functional—they do not encode protein or functional RNA, often due to mutations, deletions, or insertions that have rendered them inactive. The annotation draws on similarity to the VSIG family, whose members (for example, VSIG3, VSIG4) encode immune checkpoint or adhesion molecules implicated in immune regulation and cancer. However, ENSG00000233447 does not encode a known protein and thus lacks the biological activity of functional VSIG family members. VSIG proteins as a family can be involved in immune responses and cancer biology as receptors or ligands, but ENSG00000233447 is described exclusively as a pseudogene and does not participate in those pathways. This pseudogene designation is confirmed on authoritative gene databases, which do not attribute any normal molecular, biochemical, or therapeutic function to it. There is nothing misspelled or misleading in the designation, but it is not a therapeutic target. If your intended use involves protein-coding genes or actionable biological targets, ENSG00000233447 should be excluded.

Other names

VSIG6 pseudogenePseudogene similar to VSIG6