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This locus represents a pseudogene similar to tripartite motif-containing protein family, assigned based on DNA sequence similarities to functional genes encoding TRIM (Tripartite Motif-containing) proteins, but it is characterized by accumulated mutations, deletions, and/or loss of coding capability, rendering it non-functional for protein-coding. Pseudogenes such as this can arise from gene duplication, mutation, or retrotransposition and are generally transcriptionally silent, although some pseudogenes may be transcribed and play roles in gene regulation (such as antisense inhibition or RNA interference), but most have no known functional role or disease association[2][3][7][9]. This pseudogene is not considered a therapeutic target, and its inclusion as such is likely incorrect or at minimum misleading for drug development purposes.
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