Pseudogene similar to ubiquitin-specific peptidase 22 (ENSG00000224946)

ENSG00000224946 is a predicted pseudogene with sequence similarity to part of the ubiquitin-specific peptidase 22 (USP22) gene. Pseudogenes are nonfunctional segments of DNA that resemble functional genes but are generally incapable of encoding functional proteins due to disabling mutations such as frameshifts or premature stop codons. The specific pseudogene in question does not have evidence of producing a functional protein or acting as a classic therapeutic target (such as a receptor, enzyme, transporter, etc.). Some pseudogenes can be transcriptionally active and may have regulatory roles at the RNA level, such as producing antisense transcripts that modulate their ancestral gene or other targets, but such roles are sequence- and context-dependent and not established for every pseudogene. As such, ENSG00000224946 is not considered a valid therapeutic or biomarker target.