PSMD12 pseudogene 1 (PSMD12P1)

PSMD12 pseudogene 1 (PSMD12P1) is a non-functional pseudogene identified as related to the protein-coding PSMD12 gene, which encodes a non-ATPase regulatory subunit of the 26S proteasome. Pseudogenes like PSMD12P1 do not produce functional proteins and are not considered druggable biological targets. The gene has been identified on chromosome 3 in humans but has no known biological function, disease associations, or direct interaction with therapeutics[1][2][3]. There may be confusion with the functional PSMD12 gene, whose protein product is part of the 26S proteasome, involved in protein homeostasis, cell proliferation, apoptosis, and is relevant to cancer and neurodegenerative diseases[1][2][3]. However, PSMD12P1 is a pseudogene and should not be considered a receptor, enzyme, or other therapeutic target.

Other names

PSMD12PProteasome (prosome, macropain) 26S subunit, non-ATPase, 12 pseudogeneProteasome 26S non-ATPase subunit 12 pseudogeneProteasome 26S subunit, non-ATPase, 12 pseudogene