PSMD14 divergent transcript (PSMD14-DT)

PSMD14 divergent transcript (PSMD14-DT) is a non-coding RNA annotated at the PSMD14 locus on chromosome 2. Divergent transcripts are typically transcribed from the region upstream and in the antisense direction relative to a protein-coding gene promoter. Such transcripts are commonly referred to as uaRNAs (upstream antisense RNAs) or a type of long non-coding RNA (lncRNA), but PSMD14-DT itself does not encode a functional protein nor is it one of the established therapeutic targets such as a receptor or enzyme. While divergent transcripts can play roles in gene regulation, there is no evidence that PSMD14-DT is a drug target, biomarker, or is involved in disease pathogenesis directly. No interacting drugs, mechanisms of action, or safety concerns are reported for this transcript.