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PTGER3 antisense RNA 1 (PTGER3-AS1)
- Target
- PTGER3-AS1
- Molecular classification
- Long noncoding RNA (lncRNA), Antisense RNA, Noncoding RNA
01
Overview
PTGER3 antisense RNA 1 (PTGER3-AS1) is a long noncoding RNA that lies antisense to the PTGER3 gene, which encodes the prostaglandin EP3 receptor. Antisense RNAs like PTGER3-AS1 regulate gene expression typically by interfering with the transcription of adjacent genes, altering chromatin structure or recruiting other regulatory factors. Unlike its sense counterpart, the PTGER3 receptor, PTGER3-AS1 does not function as a receptor and is not an established pharmacological target. No known therapies, biomarkers, or drugs currently exploit PTGER3-AS1 in clinical settings[1][3][4].
- Other names
- PTGER3-AS1PTGER3 antisense RNA 1
02
Biological functions
Regulation of gene expression (especially in cis)transcriptional interferencechromatin modification
03
Disease associations
Potential regulatory involvement in diseases associated with PTGER3 expression (e.g., cancer, inflammation), but specific roles not well established for PTGER3-AS1
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