Pulmonary ventilation function

Pulmonary ventilation function refers to the physiological process by which air is moved in and out of the lungs—enabling oxygen delivery to the blood and the removal of carbon dioxide from the body. This function relies on pressure changes within the respiratory system, generated by contraction and relaxation of respiratory muscles such as the diaphragm and the intercostal muscles. Although impaired pulmonary ventilation is central to many diseases (e.g. asthma, COPD, restrictive lung disease), "pulmonary ventilation function" describes a measure of physiology, not a molecular target for direct pharmacological intervention[1][2][3][4][6][7]. There is something incorrect about this target: it is not a molecule, gene, receptor, transporter, or enzyme, and thus not a canonical therapeutic or diagnostic "target." It is a physiological process measured in clinical settings, usually as an endpoint or biomarker. Drugs and interventions that improve pulmonary ventilation typically do so by targeting molecular structures elsewhere (e.g., β2-adrenergic receptors, muscarinic receptors, ion channels)[4][5][7].

Other names

Pulmonary ventilationventilationbreathing functionventilation functionrespiratory ventilation