Purine

Purine is a heterocyclic aromatic organic compound consisting of a fused six-membered pyrimidine ring and a five-membered imidazole ring, totaling nine atoms (four nitrogens, five carbons). It forms the basic skeleton for nucleobases like adenine and guanine, essential components of DNA and RNA. Purines and their derivatives (including ATP, GTP, cAMP) play crucial roles in cellular bioenergetics, signal transduction, and serve as substrates for enzymes and receptors; they also function as neurotransmitters and secondary messengers in purinergic signaling pathways. While "purine" itself is not a pharmaceutical target, purinergic receptors and enzymes of purine metabolism are relevant drug targets in multiple diseases. If you require structured data for a therapeutic target, more precise entries would include "Adenosine receptor," "ATP synthase," or "Hypoxanthine-guanine phosphoribosyltransferase," rather than "Purine."

Other names

Purine basePurines