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Target intelligence / Profile preview
Purinergic receptor P2X 6 pseudogene (P2RX6P)
- Target
- P2RX6P
- Molecular classification
- Pseudogene, Related to ligand-gated ion channels (through homology to the functional P2X6 receptor)
01
Overview
Purinergic receptor P2X 6 pseudogene (P2RX6P) is a human pseudogene located on chromosome 22. It is homologous to the purinergic receptor P2X 6 gene (P2RX6), which is part of the family of ATP-gated ion channels, but P2RX6P itself does not encode a functional protein. It is annotated and approved as a pseudogene by the HUGO Gene Nomenclature Committee. No functional protein, biological role, or disease association is currently established for P2RX6P, and it is not recognized as a therapeutic target in drug development. Any inclusion of P2RX6P as a target for pharmacological studies should be carefully checked, as its pseudogene status means it does not encode a therapeutic or biomarker protein.
- Other names
- P2RX6PPurinergic receptor P2X 6 pseudogene
02
Mechanism of action
None relevant; no mechanism of action as a drug target due to lack of a functional protein product.
03
Biological functions
None established; as a pseudogene, P2RX6P does not encode a functional protein
04
Disease associations
None established for P2RX6P; the functional gene (P2RX6) is implicated in diseases, but the pseudogene is not known to play a role in pathogenesis
05
Safety considerations
None; as P2RX6P is a non-coding pseudogene, it does not pose direct safety concerns as a therapeutic target.
06
Interacting drugs
None
07
Biomarkers
None known; P2RX6P is not used as a biomarker for disease or drug efficacy or patient selection.
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