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The term "Qi regulation pathways" refers to the network of physiological processes proposed by Traditional Chinese Medicine as controlling the synthesis, circulation, and function of "Qi"—a concept analogous to vital energy. These pathways incorporate endocrine, metabolic, immune, and nervous system activities. Modern research attempts to connect these TCM concepts to molecular mechanisms, such as regulation of hormone secretion, neuroactive ligand-receptor interactions, metabolic flux, calcium signaling, and immune responses. However, "Qi regulation pathways" is not a discrete molecular entity and cannot be classified as a target receptor, enzyme, or protein; it is a holistic conceptual framework encompassing multiple molecular pathways that together maintain homeostasis and health[2][1][6].
Regulation of hormone secretion (thyroid, estrogen, prolactin, oxytocin); Modulation of neuroactive ligand-receptor interaction pathways (e.g., serotonergic, GABAergic synapses); Immune modulation (type I IFN signaling, lymphocyte proliferation); Regulation of metabolic enzymes and pathways (bile secretion, lipid metabolism, carbohydrate metabolism); Improved circulation and vascular smooth muscle contraction.
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