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Target intelligence / Profile preview
Queuine tRNA-ribosyltransferase catalytic subunit 1 pseudogene 1 (QTRT1P1)
- Target
- QTRT1P1
- Molecular classification
- Pseudogene (classified as a non-coding RNA, lncRNA family)
01
Overview
Queuine tRNA-ribosyltransferase catalytic subunit 1 pseudogene 1 (QTRT1P1) is a human gene classified as a pseudogene, meaning it is a non-functional copy of a protein-coding gene, in this case, QTRT1. While pseudogenes were historically considered "junk DNA," contemporary research shows some pseudogenes have indirect biological roles, such as acting as miRNA decoys or influencing the expression of related protein-coding genes. There is currently no evidence that QTRT1P1 encodes any protein or has a direct molecular function. It is not regarded as a therapeutic target, with no reported disease associations, drug interactions, or biomarker use. Biological and disease relevance described in therapeutic and cancer research pertains to QTRT1, not QTRT1P1[2][4][5]. Note: If a true biological target is needed, refer to the protein-coding QTRT1 gene, not this pseudogene.
- Other names
- Queuine tRNA-ribosyltransferase 1 pseudogene 1QTRT1P1
02
Mechanism of action
Not applicable
03
Biological functions
No direct molecular function, as pseudogenes generally do not encode functional proteins.Possible indirect roles as miRNA decoys, competing with miRNAs that may target parent genes, a role attributed to some pseudogenes in cancer and gene regulation.
04
Disease associations
No direct disease association reported for QTRT1P1.Pseudogenes (including QTRT1P1) are sometimes implicated in cancer, either as oncogenes, tumor suppressors, or miRNA decoys, but no specific disease role is validated for QTRT1P1 in current literature.
05
Safety considerations
None reported specific to QTRT1P1. There are no known safety concerns or therapeutic challenges because it is not a therapeutic target.
06
Interacting drugs
None reported
07
Biomarkers
None known
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