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Target intelligence / Profile preview
R3HDML antisense RNA 1 (R3HDML-AS1)
- Target
- R3HDML-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA, Other
01
Overview
R3HDML antisense RNA 1 (R3HDML-AS1) is a long non-coding RNA (lncRNA) gene located at chromosome 20 and is classified as an antisense RNA[1][7]. Antisense lncRNAs such as R3HDML-AS1 are known to regulate the expression of sense genes through a variety of mechanisms, including modulation of chromatin structure, transcriptional interference, and stabilization or degradation of target RNAs. The precise function of R3HDML-AS1 remains uncharacterized, but bioinformatic data links it with regulatory processes, and it is associated with Maturity-Onset Diabetes of the Young in some genetic association resources[7]. There is currently no evidence that R3HDML-AS1 itself is a direct therapeutic target (e.g., enzyme, receptor, ion channel), nor are there known drugs interacting with it or well-established roles as a biomarker, but the biology of antisense RNAs continues to be a focus of research for their gene-modulatory effects[2][6][7].
- Other names
- RP5-881L22.5ENSG00000226812105372629
02
Biological functions
Regulation of gene expressionPotential cis/trans gene regulationChromatin remodelingOther
03
Disease associations
Maturity-onset diabetes of the youngPossibly other regulatory/disease contexts (see description)
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