Rac family small GTPase 1 pseudogene 4 (RAC1P4)

Rac family small GTPase 1 pseudogene 4 (RAC1P4, or Psi4Rac1) is an intronless, non-coding sequence on human chromosome 4 with high sequence similarity to the protein-coding Rac1 gene, which is a small Rho-GTPase involved in cytoskeletal rearrangement, signaling, and cell cycle regulation[1]. RAC1P4 is one of four described Rac1 pseudogenes (psi1Rac1–psi4Rac1) found in the human genome. Like other pseudogenes of Rac1, RAC1P4 does not produce a transcript or functional protein. It is not expressed in either normal or malignant tissues, and there is no evidence that it serves a biological function or is relevant to disease. Its only significance is in genomic studies, where its existence may complicate analyses targeting the authentic Rac1 gene[1]. Clarification & Error Note: - RAC1P4 is not a druggable or therapeutic target, enzyme, receptor, or transporter; it is an unprocessed pseudogene and does not encode a functional protein. - Results may appear for the closely related active gene Rac family small GTPase 1 (RAC1), but RAC1P4 is specifically a non-functional pseudogene[1]. - Pseudogenes like RAC1P4 are sometimes annotated in genetic and genomic studies solely for reference or comparison; they have no known functional or disease relevance[1]. - If you intended the functional protein (RAC1), rather than the pseudogene, please clarify—Rac1 is an active small GTPase with established roles in signaling, cancer, and other pathologies[1][5].

Other names

Psi4Rac1psi4Rac1Rac1 pseudogene 4