Rac family small GTPase 1 pseudogene 6 (RAC1P6)

Rac family small GTPase 1 pseudogene 6 (RAC1P6) is a human pseudogene related to the RAC1 gene, which encodes a member of the Rho GTPase family involved in signal transduction and regulation of various cellular processes. As a pseudogene, RAC1P6 does not code for a functional protein, and there are no known biological or disease-related roles assigned to this specific pseudogene. In contrast, other pseudogenes from related families can participate in gene regulation (for example, acting as endogenous decoys for microRNAs—ceRNA), but no such function has been described for RAC1P6 itself. Thus, RAC1P6 is not considered a therapeutic target or valid biomarker, and it does not interact with drugs or have associated mechanisms of action. While there is published evidence that some pseudogenes, such as RACGAP1P, can have ceRNA-mediated oncogenic or tumor-suppressive roles, especially in hepatocellular carcinoma, this evidence does not extend to RAC1P6 based on available data. The existence of pseudogenes with similar names (for example, RACGAP1P—related but distinct from RAC1P6) in oncogenic pathways underscores the need to verify pseudogene function on a case-by-case basis. If the query intended RACGAP1P or another functional pseudogene, the information above would not apply—the name RAC1P6 is correct as a pseudogene but not as a therapeutic target.

Other names

RAC1P6Rac family small GTPase 1 pseudogene 6