RAD21 antisense RNA 1 (RAD21-AS1)

RAD21 antisense RNA 1 (RAD21-AS1) is a long non-protein-coding RNA transcribed from the human genome on chromosome 8, in the antisense direction to the RAD21 gene. There is little published literature on the function or disease relevance of RAD21-AS1 as of this time; most research has focused on the protein-coding RAD21 gene, which encodes a component of the cohesin complex involved in sister chromatid cohesion and DNA damage repair[1][4]. The biological function of RAD21-AS1 remains largely uncharacterized, but, as with other antisense RNAs, it may potentially influence the expression or splicing of its sense partner gene RAD21, which is implicated in cell division, cancer, and cohesinopathies[1][2][3][4]. No drugs are known to target RAD21-AS1, and it is not classified as a therapeutic target, biomarker, or receptor. Important distinction: Most functional and disease-related information in the search results pertains to RAD21, not to RAD21-AS1. The query "RAD21 antisense RNA 1" specifically refers to the noncoding RNA, which is distinct from the protein-coding RAD21 gene that forms part of the cohesin complex critical for cell division and genome integrity. The antisense RNA's role, if any, would likely be regulatory and indirect. If you intended to ask about the RAD21 protein (cohesin subunit or double-strand-break repair protein RAD21 homolog), please clarify, as much more information is available for that entity[1][4].

Other names

C8orf81NCRNA00255RAD21 antisense RNA 1 (non-protein coding)RAD21-AS1