Ras homolog family member Q pseudogene 1 (RHOQP1)

Ras homolog family member Q pseudogene 1 (**RHOQP1**) is a human pseudogene related to the RHOQ gene, which encodes a small GTPase protein of the Rho family. While the protein-coding RHOQ gene is actively involved in actin cytoskeleton regulation, cell shape, motility, and signal transduction[1][2], RHOQP1 itself is designated as a pseudogene and does not encode a functional protein. Pseudogenes are typically considered non-functional genetic elements, often remnants of once-active genes, and do not serve as direct therapeutic targets. No evidence supports its involvement in canonical signaling pathways, biological functions, or as a diagnostic or therapeutic marker. It should not be confused with RHOQ (ras homolog family member Q), which is the functional protein-coding gene and target of molecular interest in cell biology and therapeutic research[1][2]. If your interest is in the functional Rho family protein, the relevant target is "Ras homolog family member Q" (RHOQ), not "Ras homolog family member Q pseudogene 1"[1][2].