Target intelligence / Profile preview

Ras homolog family member T1 pseudogene 1 (RHOT1P1)

Target
RHOT1P1
Molecular classification
Other (Pseudogene)
01

Overview

Ras homolog family member T1 pseudogene 1 (RHOT1P1) is a human pseudogene located on chromosome 18, referenced by database accession numbers such as RHOT1P and RHOT3. It does not encode a functional protein and there is no established evidence of it serving as a therapeutic target or biomarker. No roles in disease, drug interaction, or molecular function are currently described for RHOT1P1. It is distinct from the protein-coding gene RHOT1, which encodes mitochondrial Rho GTPase 1 (MIRO1), a protein involved in mitochondrial trafficking and several pathophysiological processes.

Other names
RHOT1PRHOT3ras homolog gene family, member T1 pseudogene 1ras homolog gene family, member T3
02

Mechanism of action

None known

03

Biological functions

Currently unknown or not established; as a pseudogene, it is not known to encode a functional protein. Some pseudogenes have regulatory roles as noncoding RNA, but no evidence is available specifically for RHOT1P1.
04

Disease associations

None directly established. RHOT1P1 itself has not been linked to disease; note that the functional gene RHOT1 is implicated in cancer, neurodegeneration, and apoptosis, but RHOT1P1 is distinct from RHOT1.
05

Safety considerations

None known
06

Interacting drugs

None known
07

Biomarkers

None known

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