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Target intelligence / Profile preview
Ras-like protein family member 10A (RASL10A)
- Target
- RASL10A
- Molecular classification
- Small GTPase, Enzyme
01
Overview
Ras-like protein family member 10A (RASL10A) is a small GTPase predicted to enable GTP binding and GTPase activity, localizing primarily to the nucleolus and plasma membrane. It acts as a potent inhibitor of cellular proliferation, suggesting a possible role in tumor suppression. The gene has been implicated in inherited diseases such as Joubert syndrome 8 and Bardet-Biedl syndrome 19. There are currently no drugs reported to interact directly with this protein, and it is not recognized as a validated therapeutic target in existing public datasets
- Other names
- Ras-like protein family member 10ARASL10ARRP22Ras-like protein RRP22Ras-related protein on chromosome 22
02
Biological functions
GTPase activitySmall GTPase-mediated signal transductionInhibition of cellular proliferation
03
Disease associations
Possible tumor suppressorAssociated with Joubert syndrome 8 and Bardet-Biedl syndrome 19
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