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RBMS3 antisense RNA 2 (RBMS3-AS2) is a long non-coding RNA (lncRNA) transcribed from the antisense strand at the RBMS3 locus. It is a non-coding transcript, meaning it does not encode a protein, and is classified as an antisense RNA based on its orientation relative to the RBMS3 gene. While its precise function is not fully established in the literature, antisense lncRNAs like RBMS3-AS2 are typically involved in regulation of gene expression, often through post-transcriptional or epigenetic mechanisms. There is currently no evidence that RBMS3-AS2 itself acts as a direct therapeutic target, receptor, enzyme, transporter, or similar pharmacologically actionable entity. Its main research interest is related to the regulation of its sense gene, RBMS3, which is a known RNA-binding protein with tumor suppressor properties, especially in cancer progression and metastasis[4]. No drugs, mechanism of action, biomarkers, or therapeutic safety concerns have been linked directly to RBMS3-AS2. *Note: Most information available in the literature is about the RBMS3 protein and not about RBMS3-AS2; thus, RBMS3-AS2's functional details remain largely uncharacterized in current databases and publications. The entry is not misspelled or incorrect, but it should be clearly distinguished from the protein-coding gene RBMS3[2][4].*
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