RCC1 domain-containing protein 1 (RCCD1)

RCC1 domain-containing protein 1 (RCCD1) is a member of the RCC1 superfamily, which includes proteins characterized by the presence of one or more RCC1 (Regulator of Chromosome Condensation 1) domains. These domains are beta-propeller folds involved in mediating protein–protein interactions and have diverse roles in cellular processes, depending on the specific family member[4][5]. The canonical RCC1 protein is a known guanine nucleotide exchange factor for Ran GTPase, critical in nuclear transport and mitosis, but the precise, specific molecular function of RCCD1 itself in human biology remains largely undescribed in available expert sources[5]. There is no current evidence that RCCD1 serves as a direct therapeutic target (receptor, enzyme, transporter) in human disease. Rationale & Supporting Details - Canonical Naming: Based on gene/protein databases and structural biology conventions, "RCC1 domain-containing protein 1" is the full, standard name for RCCD1[4][5]. - Abbreviation: "RCCD1" is the accepted short form, with "MGC14386" (a legacy gene identifier) as an alias. - Is Target: No evidence indicates RCCD1 itself is a direct drug target (such as a receptor, enzyme, or transporter), nor is there database information suggesting it is a current focus in therapeutic modulation, unlike canonical RCC1[1][2]. - Aliases: All collected from gene/protein databases and the provided query. - Molecular Family: RCCD1 is part of the RCC1 superfamily and more broadly fits under "Other" as a classification, since it does not fall under the standard classes like enzyme, receptor, etc.[4][5]. - Biological Functions: Unlike canonical RCC1, which is well characterized, RCCD1-specific biological function in humans is not well documented in the literature and major databases. All descriptions point only to its domain structure and potential for diverse protein/protein interactions[5]. - Disease Roles, Drugs, Biomarkers, Safety, Mechanism: No evidence or mention is found in the literature or major gene/protein resources for RCCD1 as a disease-associated gene, drug target, or biomarker. No interacting drugs or safety concerns are documented. - Description: Provided based on domain family characteristics, emphasizing the lack of direct experimental or clinical role for RCCD1 in humans in current sources.

Other names

RCCD1MGC14386RCC1 domain containing 1RCC1 domain-containing protein 1