Reactive oxygen species, intracellular (ROS (contextually, but no specific standardized abbreviation for the intracellular pool))

Intracellular reactive oxygen species are small, chemically reactive molecules derived from oxygen and generated within the cell—primarily by mitochondrial respiration, NADPH oxidases, peroxisomes, and other organelles. They act as both signaling molecules regulating processes such as proliferation, differentiation, and apoptosis, and as effectors of cellular damage when present at high concentrations. Dysregulation of intracellular ROS production and removal is implicated in a wide variety of diseases, including cancer, inflammation, neurodegeneration, cardiovascular disease, and aging. While drugs may target pathways that generate or scavenge ROS, "intracellular reactive oxygen species" does not refer to a distinct, molecule-specific therapeutic target[1][2][3].

Other names

ROS (Reactive oxygen species)Intracellular ROS

Scavenging ROS, Inhibiting ROS production, Modulating redox-sensitive signaling pathways, Enhancing ROS for cytotoxic effect (in cancer therapy)