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Recipient cell signaling pathways refer to the complex networks of intracellular biochemical events triggered in a recipient (target) cell in response to extracellular signals—typically beginning with the binding of a ligand (such as a hormone, growth factor, or neurotransmitter) to a specific cell-surface or intracellular receptor[1][2][3][7]. These pathways mediate information flow from the cell surface to the nucleus or other cellular compartments, resulting in diverse cellular responses, including alterations in gene expression, metabolism, cell growth, division, or death[1][2][3][4][5][6]. Major classes include G protein-coupled receptor signaling, receptor tyrosine kinase pathways, ion channel-linked signaling, and nuclear receptor signaling, among others[2][3][5][7]. These processes are fundamental to normal physiology and development, and their disruption is implicated in diseases such as cancer, metabolic syndrome, inflammation, and neurological disorders[4][6][7].
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