Recipient cell surface molecules

Recipient cell surface molecules encompass a diverse and context-dependent collection of membrane-bound proteins, glycoproteins, lipids, and polysaccharides found on the surface of cells that act as points of interaction for extracellular entities. In mammalian systems, these include broad classes such as receptors (GPCRs, tyrosine kinases, cytokine receptors), ion channels, and adhesion molecules involved in signal transduction, vesicle uptake, and cell-cell communication[2][1][4]. In microbial contexts, specific outer membrane proteins, lipopolysaccharides, and polysaccharides serve as receptors for conjugation machinery and horizontal transfer of genetic material[5][6]. These molecules are not a single target but represent a functional group essential for processes like extracellular vesicle uptake, immune modulation, and microbial gene transfer[1][2][5]. This term should not be used as a canonical entry for a therapeutic target; rather, individual surface molecules (such as “Programmed cell death protein 1,” “CD44,” “OmpA,” etc.) should be referenced and structured for database use[3][5][6].

Other names

cell surface moleculecell surface receptorrecipient membrane proteinconjugation receptorexofacial marker

Uptake of extracellular vesicles via fusion or endocytosis; Receptor-ligand binding leading to signal transduction; Adhesin-receptor interaction in bacterial conjugation