Redox balance normalization

Redox balance normalization refers to the restoration and maintenance of the equilibrium between oxidant production (e.g., reactive oxygen species, reactive nitrogen species) and antioxidant defenses in biological systems[1][4][5][6]. This balance is central to numerous physiological processes, including metabolism, cell signaling, immune defense, and gene regulation. Disruption of redox homeostasis, leading to either oxidative or reductive stress, is implicated in the pathogenesis of many diseases such as cancer, neurodegenerative disorders, cardiovascular disease, and inflammation[5][6]. While redox balance is regulated by complex systems (such as the glutathione and thioredoxin systems, and enzymes like superoxide dismutase and catalase), "redox balance normalization" itself is not a protein, receptor, or single drug target, but denotes an overall biochemical state or therapeutic goal[1][3][6]. "Redox balance normalization" is not a molecular target but a functional state/process, making it unsuitable for use as a canonical drug target entity. The term aligns with "redox homeostasis" or "redox regulation," indicating a physiological process rather than a singular therapeutic target[1][4][5][6].

Other names

Redox homeostasisRedox regulationRedox equilibriumOxidative stress balanceRedox state balance