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The anti-inflammatory effect refers to the property of a substance, molecule, or treatment that reduces inflammation—characterized by redness, swelling, pain, and sometimes loss of function—in tissues or organs. This effect is achieved by blocking or modulating specific biological pathways that drive the inflammatory response, such as inhibiting proinflammatory mediators like cytokines (e.g., TNF-α, IL-1β), enzymes (e.g., cyclooxygenase), and transcription factors (e.g., NF-κB).
Various mechanisms including inhibition of cyclooxygenase (COX) enzymes, modulation of gene expression via glucocorticoid receptor, neutralization of specific cytokines/receptors, and modulation of eicosanoid synthesis.
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