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Regeneration

01

Overview

**Regeneration** is a natural biological process wherein organisms restore, replace, or regrow missing or damaged cellular structures, tissues, or organs. The process is central to the maintenance of tissues and organs across all species, but the extent and type of regeneration vary widely—from complete limb or organ regrowth in certain animals like salamanders and planarians, to limited tissue repair in humans (e.g., liver and skin)[1][2][3][8]. Key mechanisms include proliferation of stem or progenitor cells, dedifferentiation of mature cells, and the activation of specific genetic pathways such as Wnt/β-catenin[6]. While not a druggable molecular target, regeneration is the main focus of regenerative medicine—a field aiming to harness or mimic these natural processes in humans to treat injuries or degenerative conditions[2][8]. **Note:** "Regeneration" is a biological process, not a molecular target, receptor, enzyme, or other single molecular entity. Any attempt to use "Regeneration" as a therapeutic target identifier would be incorrect or misleading in biomedical data structuring.

Other names
Regenerative processBiological regenerationTissue regeneration
02

Biological functions

Renewal of cells and tissuesRestoration of organ functionTissue repairCell proliferationMorphogenesisDifferentiation
03

Disease associations

Injury recoveryOrgan regeneration (e.g., liver)Degenerative diseases researchRegenerative medicine

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