Regulation of arginine and proline metabolism

The "regulation of arginine and proline metabolism" refers to the coordinated enzymatic and physiological control over the metabolic pathways that interconvert arginine, proline, glutamate, ornithine, and related intermediates. These pathways are essential for amino acid biosynthesis, urea cycle function, redox balance, and, in some contexts, the production of signaling molecules such as nitric oxide. Dysregulation of this axis, particularly at specific enzymes, has been implicated in the progression of cancer and other diseases. Important Caveat: This entry describes a metabolic pathway/process rather than a direct, clinically actionable drug target, receptor, or molecular entity. If you are seeking structured data for a therapeutically actionable target within this pathway (such as "Arginase-1," "Pyrroline-5-carboxylate reductase," or "Ornithine aminotransferase"), you should specify the individual enzyme or protein. The current entry is too broad by the conventions for drug target annotation and would be marked as requiring correction.

Other names

Arginine and proline metabolism pathwayArginine-proline metabolic axisGlutamine-arginine-proline metabolism axis