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The phrase "Regulation of qi flow in respiratory tract per TCM theory" does not refer to a discrete molecular entity, receptor, enzyme, transporter, or specific biological target recognized in biomedical science. Instead, it describes a holistic theoretical concept from Traditional Chinese Medicine (TCM), where "qi" denotes a vital energy or life force considered essential for health. In TCM, the lungs are viewed as governing the flow of qi through the respiratory system, and imbalances in this flow are believed to underlie various respiratory conditions such as asthma, bronchitis, and COPD[1][2][3][4][5][9]. The regulation of qi is conceptual, addressed through interventions like acupuncture, herbal medicine, and lifestyle adjustment rather than through drug interaction with a biochemical target[4][5][7]. Accordingly, this term should not be interpreted as a druggable target or molecular entity but as a traditional, non-molecular conceptual framework used in TCM to guide diagnosis and therapy[3][4][6][8][9].
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