Removing Blood Stasis

Removing Blood Stasis (Huoxue Huayu) is a fundamental therapeutic principle in Traditional Chinese Medicine (TCM) used to treat conditions characterized by impaired blood flow, fixed pain, or abnormal masses [World Journal of Traditional Chinese Medicine, 2020]. It is not a single molecular target, receptor, or enzyme, but rather a pharmacological category that encompasses a wide range of biological activities aimed at restoring normal circulation. Modern pharmacological research indicates that herbs and formulas with this property exert their effects through multiple molecular pathways, such as inhibiting platelet aggregation, promoting fibrinolysis, and improving endothelial function [PubMed: 30553153]. Common clinical applications include the treatment of cardiovascular diseases, stroke, and chronic inflammatory conditions. Because it represents a broad therapeutic strategy rather than a specific protein or gene, it cannot be classified as a discrete molecular target in the conventional drug discovery sense.

Other names

Huoxue HuayuActivating blood circulation and removing blood stasisPromoting blood circulation to dissipate blood stasisBlood-stasis-removing therapy

This is a therapeutic principle in Traditional Chinese Medicine (TCM) rather than a single molecular mechanism. It involves multi-target effects including the inhibition of platelet activation (via TXA2/PGI2 balance), reduction of blood viscosity, modulation of the coagulation cascade, and improvement of endothelial function [PubMed: 28655521, Frontiers in Pharmacology 2019].