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Target intelligence / Profile preview
Renal Cortical Cell
- Molecular classification
- Cell
01
Overview
Renal cortical cells are the primary cell types found in the renal cortex, which is the outer region of the kidney. The renal cortex contains key structures involved in blood filtration and urine formation, including glomeruli, proximal convoluted tubules (PCT), distal convoluted tubules (DCT), and associated blood vessels. These cells play essential roles in maintaining homeostasis by filtering blood, reabsorbing nutrients, secreting waste products, and producing hormones. Dysfunction of these cells is implicated in various diseases, including acute kidney injury and chronic kidney disease.
- Other names
- HRCEpiCHuman Renal Cortical Epithelial CellsGlomerular cellsProximal convoluted tubular epithelial cellsDistal convoluted tubular epithelial cellsParietal epithelial cells of Bowman’s capsule
02
Mechanism of action
N/A
03
Biological functions
FiltrationReabsorptionSecretionHormone ProductionRegulation of blood pressureElectrolyte balance
04
Disease associations
Acute kidney injury (AKI)Chronic kidney disease (CKD)Crescentic glomerulonephritisInflammationKidney disease
05
Biomarkers
IL-2R alphaMHC class II antigens
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