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Replication factor C 5 pseudogene 1 (RFC5P1)

Target: RFC5P1
Molecular classification: Other (Pseudogene)

Overview

Replication factor C 5 pseudogene 1 (RFC5P1) is a pseudogene classified as a non-coding sequence in the human genome that is homologous to the protein-coding replication factor C subunit 5 (RFC5) but does not encode a functional protein[8]. True RFC5 is a core subunit of the replication factor C complex, an essential DNA clamp loader required for DNA replication and repair, but RFC5P1 does not perform these molecular functions. Thus, RFC5P1 is not considered a therapeutic target, and there are no drugs, disease associations, or clinical biomarkers linked specifically to it. RFC5P1 is frequently confused with the true RFC5, a well-characterized and essential ATPase component of the DNA replication machinery. However, as a pseudogene, RFC5P1 has no known encoding or regulatory role in protein function or disease and is not recognized as a drug target or biomarker[8]. If you seek information regarding the functional replication factor C subunit 5 (RFC5, not "RFC5P1"), please specify, as the properties, classification, and clinical relevance differ entirely between pseudogenes and true protein-coding genes[5][4].

Other names: RFC5P1Replication Factor C Subunit 5 Pseudogene 1

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