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RERE antisense RNA 1 (RERE-AS1)
- Target
- RERE-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Natural antisense transcript (NAT)
01
Overview
RERE antisense RNA 1 (RERE-AS1) is a long non-coding RNA transcribed from the antisense DNA strand overlapping the RERE gene. As a member of the natural antisense transcript (NAT) family, RERE-AS1 likely regulates gene expression through mechanisms such as transcriptional interference, chromatin modification, and post-transcriptional RNA interactions[1][2]. Like other antisense RNAs, RERE-AS1 potentially modulates the expression of its sense counterpart gene, RERE, with possible roles in epigenetic regulation and disease pathogenesis, especially cancer. However, direct experimental evidence and deep functional annotation for RERE-AS1 are currently lacking.
- Other names
- RERE-AS1RP11-326I13.3
02
Biological functions
Regulation of gene expression (transcriptional, post-transcriptional)Possible involvement in epigenetic regulation (based on general antisense RNA mechanisms)Modulation of chromatin structure and transcriptional interference (by analogy to other antisense RNAs)
03
Disease associations
CancerOther roles remain unclear due to limited direct evidence for RERE-AS1
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